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Found 4 Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50293087'
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50293087(2-amino-7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyr...)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of human PNP by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50293087(2-amino-7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyr...)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of human His-tagged PNP assessed as equilibrium dissociation constant by measuring reduction in uric acid formation by spectrophotometric ...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50293087(2-amino-7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyr...)
Affinity DataKi:  0.160nMAssay Description:Inhibition of human His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor complex formation by measuring reduction in uric acid formatio...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£

Curated by ChEMBL
LigandPNGBDBM50293087(2-amino-7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyr...)
Affinity DataKi:  0.890nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP expressed in Escherichia coli assessed as inhibitor constant for enzyme-inhibitor complex formatio...More data for this Ligand-Target Pair