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Found 2 Enz. Inhib. hit(s) with Target = 'Receptor tyrosine-protein kinase erbB-2' and Ligand = 'BDBM50205268'
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50205268(ARRY-334543 | ARRY-543 | ASLAN-001 | Varlitinib)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant His-tagged HER2 (catalytic domain 691 to 1255 residues) using polyglutamic acid/tyrosine as substrate by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50205268(ARRY-334543 | ARRY-543 | ASLAN-001 | Varlitinib)
Affinity DataIC50:  2nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed