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Found 8 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM420295'
TargetReplicase polyprotein 1ab(2019-nCoV)
Bio-Techne (Tocris)

Curated by ChEMBL
LigandPNGBDBM420295(alpha-ketoamide inhibitor 13b | med.21724, Compoun...)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant SARS-COV2 main protease using DabcylKTSAVLQISGFRKM-E(Edans)-N1-as substrate by FRET assayMore data for this Ligand-Target Pair
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In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Bio-Techne (Tocris)

Curated by ChEMBL
LigandPNGBDBM420295(alpha-ketoamide inhibitor 13b | med.21724, Compoun...)
Affinity DataIC50:  670nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Bio-Techne (Tocris)

Curated by ChEMBL
LigandPNGBDBM420295(alpha-ketoamide inhibitor 13b | med.21724, Compoun...)
Affinity DataIC50:  670nMAssay Description:Inhibition of recombinant SARS-CoV-2 Main proteaseMore data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Bio-Techne (Tocris)

Curated by ChEMBL
LigandPNGBDBM420295(alpha-ketoamide inhibitor 13b | med.21724, Compoun...)
Affinity DataIC50:  670nMAssay Description:Inhibition of C-terminal 6-His-tagged recombinant SARS CoV-2 3CL protease expressed in Escherichia coli BL21-Gold DE3 cells by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Bio-Techne (Tocris)

Curated by ChEMBL
LigandPNGBDBM420295(alpha-ketoamide inhibitor 13b | med.21724, Compoun...)
Affinity DataIC50:  900nMAssay Description:Inhibition of C-terminal 6-His-tagged recombinant SARS CoV 3CL protease expressed in Escherichia coli BL21-Gold DE3 cells by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM420295(alpha-ketoamide inhibitor 13b | med.21724, Compoun...)
Affinity DataIC50:  900nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM420295(alpha-ketoamide inhibitor 13b | med.21724, Compoun...)
Affinity DataEC50:  1.75E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Bio-Techne (Tocris)

Curated by ChEMBL
LigandPNGBDBM420295(alpha-ketoamide inhibitor 13b | med.21724, Compoun...)
Affinity DataEC50:  4.50E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed