Found 3 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM50378739' 
Affinity DataIC50: 260nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 278nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Montpellier
University Of Montpellier
Affinity DataIC50: 360nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
