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Found 2 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50004421'
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004421(CHEMBL3238166)
Affinity DataIC50:  65nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004421(CHEMBL3238166)
Affinity DataEC50:  416nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed