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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha-3' and Ligand = 'BDBM50361859'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM50361859
PNG
(CHEMBL1938772)
Show SMILES O=C(Nc1cccnc1)c1ccc2cc3C(=O)NCC4(CCOCC4)Cn3c2c1
Show InChI InChI=1S/C22H22N4O3/c27-20(25-17-2-1-7-23-12-17)16-4-3-15-10-19-21(28)24-13-22(5-8-29-9-6-22)14-26(19)18(15)11-16/h1-4,7,10-12H,5-6,8-9,13-14H2,(H,24,28)(H,25,27)
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MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of RSK2 phosphorylation by luminescence assay


Bioorg Med Chem Lett 22: 733-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.030
BindingDB Entry DOI: 10.7270/Q2XW4K7N
More data for this
Ligand-Target Pair