Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'S-adenosylmethionine synthase isoform type-2' and Ligand = 'BDBM85447'
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire de chimie bioorganique

LigandPNGBDBM85447(Epoxy analogue, I(a))
Show SMILES N[C@@H](C[C@H]1CO1)C(O)=O
Show InChI InChI=1S/C5H9NO3/c6-4(5(7)8)1-3-2-9-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4-/m0/s1
Affinity DataKi:  7.00E+3nM ΔG°:  -30.6kJ/mole IC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair