Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'S-adenosylmethionine synthase isoform type-2' and Ligand = 'BDBM85448'
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire de chimie bioorganique

LigandPNGBDBM85448(Epoxy analogue, I(b))
Show SMILES C[C@H]1O[C@H]1C[C@H](N)C(O)=O
Show InChI InChI=1S/C6H11NO3/c1-3-5(10-3)2-4(7)6(8)9/h3-5H,2,7H2,1H3,(H,8,9)/t3-,4+,5+/m1/s1
Affinity DataKi:  6.10E+4nM ΔG°:  -25.0kJ/mole IC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair