BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'SUMO-activating enzyme subunit 2 (SAE2)' and Ligand = 'BDBM50439438'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SUMO-activating enzyme subunit 2 (SAE2)


(Homo sapiens (Human))
BDBM50439438
PNG
(CHEMBL1448459)
Show SMILES Clc1ccc2c(Oc3ccc(NC(=O)Nc4ccccc4)cn3)ncnc2c1
Show InChI InChI=1S/C20H14ClN5O2/c21-13-6-8-16-17(10-13)23-12-24-19(16)28-18-9-7-15(11-22-18)26-20(27)25-14-4-2-1-3-5-14/h1-12H,(H2,25,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.73E+4n/an/an/an/an/an/a



RIKEN

Curated by ChEMBL


Assay Description
Inhibition of SUMO E1 (unknown origin)-mediated RanGAP1 sumoylation by immunoblotting analysis


Bioorg Med Chem Lett 23: 5145-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.022
BindingDB Entry DOI: 10.7270/Q2WD4205
More data for this
Ligand-Target Pair