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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'SUMO-activating enzyme subunit 2 (SAE2)' and Ligand = 'BDBM50439439'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SUMO-activating enzyme subunit 2 (SAE2)


(Homo sapiens (Human))
BDBM50439439
PNG
(CHEMBL1900956)
Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(Oc3ncnc4cc(Cl)ccc34)nc2)c1
Show InChI InChI=1S/C21H13ClF3N5O2/c22-13-4-6-16-17(9-13)27-11-28-19(16)32-18-7-5-15(10-26-18)30-20(31)29-14-3-1-2-12(8-14)21(23,24)25/h1-11H,(H2,29,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.56E+4n/an/an/an/an/an/a



RIKEN

Curated by ChEMBL


Assay Description
Inhibition of SUMO E1 (unknown origin)-mediated RanGAP1 sumoylation by immunoblotting analysis


Bioorg Med Chem Lett 23: 5145-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.022
BindingDB Entry DOI: 10.7270/Q2WD4205
More data for this
Ligand-Target Pair