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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Aurora-C' and Ligand = 'BDBM50218901'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase Aurora-C


(Homo sapiens (Human))
BDBM50218901
PNG
(7-fluoroindirubin-3-methoxime | CHEMBL397720)
Show SMILES CO\N=C1/C(/Nc2ccccc/12)=C1/C(=O)Nc2c1cccc2F
Show InChI InChI=1S/C17H12FN3O2/c1-23-21-15-9-5-2-3-8-12(9)19-16(15)13-10-6-4-7-11(18)14(10)20-17(13)22/h2-8,19H,1H3,(H,20,22)/b16-13-,21-15-
PDB

NCI pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of human recombinant aurora C kinase


J Med Chem 50: 4027-37 (2007)


Article DOI: 10.1021/jm070077z
BindingDB Entry DOI: 10.7270/Q2PC323X
More data for this
Ligand-Target Pair