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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Aurora-C' and Ligand = 'BDBM50352297'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase Aurora-C


(Homo sapiens (Human))
BDBM50352297
PNG
(CHEMBL1822485)
Show SMILES Cc1cc(Nc2nc(Sc3ccc(NC(=O)C4CC4)cc3)nn3cccc23)n[nH]1
Show InChI InChI=1S/C20H19N7OS/c1-12-11-17(25-24-12)22-18-16-3-2-10-27(16)26-20(23-18)29-15-8-6-14(7-9-15)21-19(28)13-4-5-13/h2-3,6-11,13H,4-5H2,1H3,(H,21,28)(H2,22,23,24,25,26)
PDB

NCI pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/a 4n/an/an/an/an/a



Ambit Biosciences Corporation

Curated by ChEMBL


Assay Description
Binding affinity to Aurora C kinase catalytic domain by competitive binding assay


Bioorg Med Chem Lett 21: 5296-300 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.027
BindingDB Entry DOI: 10.7270/Q20P10D8
More data for this
Ligand-Target Pair