Found 7 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK2' and Ligand = 'BDBM25121' 
Affinity DataKi: <1nMAssay Description:Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 14nMAssay Description:Inhibition human recombinant full length GST-tagged Plk2 expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant full length human GST-tagged PLK2 expressed in baculovirus expression system using ser/thr 16 as substrate incubated for 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 16.8nMpH: 7.5 T: 2°CAssay Description:Percent inhibition and IC50 values were determined with ATP concentrations at apparent Km using the Invitrogen SelectScreen Kinase Profiling Service ...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human PLK2 (65 to 409 resiudes) using casein as substrate incubated for 40 mins in the presence of [gamma33P]ATP at Km conc...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.More data for this Ligand-Target Pair
Affinity DataKd: 0.810nMAssay Description:Binding constant for PLK2 kinase domainMore data for this Ligand-Target Pair
