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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor' and Ligand = 'BDBM50047889'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50047889
PNG
(1-Butyl-4-hydroxy-2-oxo-1,2-dihydro-[1,8]naphthyri...)
Show SMILES CCCCn1c2ncccc2c(O)c(C(=O)OC2CC3CCC(C2)N3C)c1=O
Show InChI InChI=1S/C21H27N3O4/c1-3-4-10-24-19-16(6-5-9-22-19)18(25)17(20(24)26)21(27)28-15-11-13-7-8-14(12-15)23(13)2/h5-6,9,13-15,25H,3-4,7-8,10-12H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>100n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.


J Med Chem 36: 617-26 (1993)


Article DOI: 10.1021/jm00057a011
BindingDB Entry DOI: 10.7270/Q25B034N
More data for this
Ligand-Target Pair