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Found 3 Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50006968'
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006968((3-Phenyl-propyl)-(6,7,8,9-tetrahydro-5H-benzocycl...)
Affinity DataKi:  7.90nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50006968((3-Phenyl-propyl)-(6,7,8,9-tetrahydro-5H-benzocycl...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006968((3-Phenyl-propyl)-(6,7,8,9-tetrahydro-5H-benzocycl...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro binding affinity at PCP binding site of Sigma opioid receptor using (+)-[3H]-NANM as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed