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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM22415'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

LigandPNGBDBM22415(5-(3,4-dimethoxyphenyl)-2-[(1R,2S,3S,5S)-8-methyl-...)
Affinity DataKi:  529nM EC50:  885nMAssay Description:Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

LigandPNGBDBM22415(5-(3,4-dimethoxyphenyl)-2-[(1R,2S,3S,5S)-8-methyl-...)
Affinity DataIC50:  83nMpH: 7.4 T: 2°CAssay Description:Brains from male Sprague-Dawley rats were removed, dissected, and rapidly frozen. Ligand binding experiments were conducted in assay tubes containing...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed