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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM22402'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

LigandPNGBDBM22402(5-(3-bromophenyl)-2-[(1R,2S,3S,5S)-3-(4-chlorophen...)
Affinity DataKi:  280nM ΔG°:  -37.4kJ/molepH: 7.4 T: 2°CAssay Description:Brains from male Sprague-Dawley rats were removed, dissected, and rapidly frozen. Ligand binding experiments were conducted in assay tubes containing...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

LigandPNGBDBM22402(5-(3-bromophenyl)-2-[(1R,2S,3S,5S)-3-(4-chlorophen...)
Affinity DataKi:  1.50E+3nM EC50:  4.00E+3nMAssay Description:Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed