Found 24 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM84745' TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 0.790nMAssay Description:Ability to inhibit [3H]-paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 0.800nMAssay Description:Ability to inhibit the reuptake of 5-HT at human serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 4.60nMAssay Description:Inhibition constant against serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 5nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 5nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 0.316nMAssay Description:Inhibition of human recombinant SERT expressed in HEK293 cells assessed as inhibition of [3H]5HT reuptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 3nMAssay Description:Inhibition of human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]5-HT reuptake at 5HT transporter in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]5HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human SERTMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 6.60nMAssay Description:Displacement of [alpha,beta-3H(N)]-5-hydroxytryptamine from human cloned SERT expressed in HEK293 cells by microplate scintillation counterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 10nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells after 15 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 10nMAssay Description:Inhibition of human SERT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataIC50: 515nMAssay Description:Inhibition of human NET expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
