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Found 9 Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 12' and Ligand = 'BDBM290431'
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM290431(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM290431(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells by assessed as [14C]urate uptake preincubated for 5 mins followed by [14C]urate addition and mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM290431(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Affinity DataIC50: <50nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM290431(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Affinity DataIC50: <100nMAssay Description:Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM290431(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Affinity DataIC50: <100nMAssay Description:Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM290431(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Affinity DataIC50:  113nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM290431(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Affinity DataIC50: >1.00E+3nMAssay Description:Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM290431(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Affinity DataEC50:  26nMAssay Description:HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
West China Hospital Of Sichuan University

Curated by ChEMBL
LigandPNGBDBM290431(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Affinity DataEC50:  25nMAssay Description:HEK293 human embryonic kidney cells (ATCC #CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% C02 an...More data for this Ligand-Target Pair
In DepthDetails US Patent