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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 6' and Ligand = 'BDBM50344964'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 6


(Homo sapiens)
BDBM50344964
PNG
(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)
Show SMILES OC(=O)CCNC(=O)c1ccccc1
Show InChI InChI=1S/C10H11NO3/c12-9(13)6-7-11-10(14)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)
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Article
PubMed
2.36E+4n/an/an/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells


Eur J Pharmacol 419: 113-20 (2001)


Article DOI: 10.1016/s0014-2999(01)00962-1
BindingDB Entry DOI: 10.7270/Q2S183SP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 6


(Homo sapiens)
BDBM50344964
PNG
(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)
Show SMILES OC(=O)CCNC(=O)c1ccccc1
Show InChI InChI=1S/C10H11NO3/c12-9(13)6-7-11-10(14)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)
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Article
PubMed
2.36E+4n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of human Oat1 expressed in Drosophila S2 cells


Bioorg Med Chem 19: 3320-40 (2011)


Article DOI: 10.1016/j.bmc.2011.04.045
BindingDB Entry DOI: 10.7270/Q2TB17WF
More data for this
Ligand-Target Pair
Solute carrier family 22 member 6


(Homo sapiens)
BDBM50344964
PNG
(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)
Show SMILES OC(=O)CCNC(=O)c1ccccc1
Show InChI InChI=1S/C10H11NO3/c12-9(13)6-7-11-10(14)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)
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PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



Gilead Sciences

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Adefovir uptake in OAT1-expressing CHO cells


J Pharmacol Exp Ther 295: 10-5 (2000)


BindingDB Entry DOI: 10.7270/Q2TB186W
More data for this
Ligand-Target Pair
Solute carrier family 22 member 6


(Homo sapiens)
BDBM50344964
PNG
(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)
Show SMILES OC(=O)CCNC(=O)c1ccccc1
Show InChI InChI=1S/C10H11NO3/c12-9(13)6-7-11-10(14)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)
Reactome pathway
KEGG

UniProtKB/SwissProt

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CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

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Article
PubMed
n/an/a 3.90E+4n/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cells


J Pharmacol Sci 94: 197-202 (2004)


Article DOI: 10.1254/jphs.94.197
BindingDB Entry DOI: 10.7270/Q27M0915
More data for this
Ligand-Target Pair