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Found 3 Enz. Inhib. hit(s) with Target = 'Somatostatin receptor type 4' and Ligand = 'BDBM523754'
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523754(US11136312, Compound MM-I-66)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523754(US11136312, Compound MM-I-66)
Affinity DataKi:  0.825nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM523754(US11136312, Compound MM-I-66)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at recombinant human SST4 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed