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Found 2 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM50313339'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313339(6-(cyclohexyl(propyl)amino)-N-(2-methyl-4-sulfamoy...)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313339(6-(cyclohexyl(propyl)amino)-N-(2-methyl-4-sulfamoy...)
Affinity DataEC50:  2.90nMpH: 7.4 T: 2°CAssay Description:Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...More data for this Ligand-Target Pair
In DepthDetails US Patent