Found 4 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM50357781' TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 4.60nMAssay Description:Agonist activity at human S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 39nMAssay Description:Agonist activity at recombinant human S1P1 receptor expressed in HEK293 cells after 2 hrs by beta-arrestin assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Agonist activity at rat S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF ass...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at mouse S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...More data for this Ligand-Target Pair
