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Found 2 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 3' and Ligand = 'BDBM50277148'
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277148((S)-2-amino-2-methyl-3-(4-(octyloxy)phenylamino)-3...)
Affinity DataIC50:  5.90nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277148((S)-2-amino-2-methyl-3-(4-(octyloxy)phenylamino)-3...)
Affinity DataEC50:  16.3nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed