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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase, Soat' and Ligand = 'BDBM50038920'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)		BDBM50038920
PNG
(1-[6-Chloro-4-(2-chloro-phenyl)-8-methyl-quinolin-...)
Show SMILES Cc1cc(Cl)cc2c(c(NC(=O)Nc3ccc(F)cc3F)cnc12)-c1ccccc1Cl
Show InChI InChI=1S/C23H15Cl2F2N3O/c1-12-8-13(24)9-16-21(15-4-2-3-5-17(15)25)20(11-28-22(12)16)30-23(31)29-19-7-6-14(26)10-18(19)27/h2-11H,1H3,(H2,29,30,31)
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomes

J Med Chem 37: 2079-84 (1994)


Article DOI: 10.1021/jm00039a020
BindingDB Entry DOI: 10.7270/Q23F4NPC
More data for this
Ligand-Target Pair