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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase, Soat' and Ligand = 'BDBM50063226'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50063226
PNG
(CHEMBL160149 | N-(2,6-Diisopropyl-phenyl)-2-phenyl...)
Show SMILES CCCCC(C)(C)OC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C28H39NO3/c1-8-9-18-28(6,7)32-27(31)24(21-14-11-10-12-15-21)26(30)29-25-22(19(2)3)16-13-17-23(25)20(4)5/h10-17,19-20,24H,8-9,18H2,1-7H3,(H,29,30)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats


J Med Chem 41: 682-90 (1998)


Article DOI: 10.1021/jm970560h
BindingDB Entry DOI: 10.7270/Q28051R8
More data for this
Ligand-Target Pair