BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase, Soat' and Ligand = 'BDBM50450333'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50450333
PNG
(CHEMBL48094)
Show SMILES CCCCCCN(CCCCCSc1nc2c[nH]cnc2n1)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C23H30F2N6OS/c1-2-3-4-6-11-31(23(32)29-19-10-9-17(24)14-18(19)25)12-7-5-8-13-33-22-28-20-15-26-16-27-21(20)30-22/h9-10,14-16H,2-8,11-13H2,1H3,(H,29,32)(H,26,27,28,30)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

n/an/a 860n/an/an/an/an/an/a



The DuPont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomes by using AIV assay.


Bioorg Med Chem Lett 5: 167-72 (1995)


BindingDB Entry DOI: 10.7270/Q2Z03833
More data for this
Ligand-Target Pair