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Found 15 Enz. Inhib. hit(s) with Target = 'Steryl-sulfatase' and Ligand = 'BDBM50136297'
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibitory constant against human steroid sulfatase in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.150nMAssay Description:Inhibitory activity against human steroid sulfatase in sebocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of estrone sulfatase in human sebocytes using DHEAS as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.75nMAssay Description:Inhibitory activity against human steroid sulfatase expressing in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of estrone sulfatase human keratinocytes using DHEAS as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of human STS in keratinocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of estrone sulfatase in human MCF7 cells using estrone sulphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of estrone sulfatase in human skin fibroblasts using DHEAS as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against STS in human MCF-7 breast cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  32nMAssay Description:Inhibitory constant against human steroid sulfatase in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human estrone sulfatase expressed in CHO cells using estrone sulphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  970nMAssay Description:Inhibition of human aryl sulfatase using p-nitrocatechol sulfate as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Forschungsinstitut

Curated by ChEMBL
LigandPNGBDBM50136297(CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...)
Affinity DataIC50:  970nMAssay Description:Inhibition of steroid sulfatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed