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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sulfonylurea receptor 2, Kir6.2' and Ligand = 'BDBM50247612'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247612
PNG
((3S,4R)-4-(5-Ethoxy-benzothiazol-2-ylamino)-3-hydr...)
Show SMILES CCOc1ccc2nc(S[C@H]3[C@H](O)C(C)(C)Oc4ccc(cc34)C#N)[nH]c2c1
Show InChI InChI=1S/C21H21N3O3S/c1-4-26-13-6-7-15-16(10-13)24-20(23-15)28-18-14-9-12(11-22)5-8-17(14)27-21(2,3)19(18)25/h5-10,18-19,25H,4H2,1-3H3,(H,23,24)/t18-,19+/m1/s1
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PC cid
PC sid
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Article
PubMed
n/an/an/an/a 2.60E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Citation and Details
More data for this
Ligand-Target Pair