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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sulfonylurea receptor 2, Kir6.2' and Ligand = 'BDBM50247649'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247649
PNG
((3S,4R)-3-Hydroxy-2,2-dimethyl-4-(5-nitrobenzothia...)
Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Sc2nc3ccc(cc3[nH]2)[N+]([O-])=O)[C@@H]1O)C#N
Show InChI InChI=1S/C19H16N4O4S/c1-19(2)17(24)16(12-7-10(9-20)3-6-15(12)27-19)28-18-21-13-5-4-11(23(25)26)8-14(13)22-18/h3-8,16-17,24H,1-2H3,(H,21,22)/t16-,17+/m1/s1
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Article
PubMed
n/an/an/an/a 3.09E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Bioorg Med Chem 17: 855-66 (2009)

More data for this
Ligand-Target Pair