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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sulfonylurea receptor 2, Kir6.2' and Ligand = 'BDBM50247724'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247724
PNG
((3S,4R)-4-[2-(4-Chloro-phenyl)-imidazol-1-yl]-3-hy...)
Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1ccnc1-c1ccc(Cl)cc1)C#N
Show InChI InChI=1S/C21H18ClN3O2/c1-21(2)19(26)18(16-11-13(12-23)3-8-17(16)27-21)25-10-9-24-20(25)14-4-6-15(22)7-5-14/h3-11,18-19,26H,1-2H3/t18-,19+/m1/s1
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Article
PubMed
n/an/an/an/a 2.75E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Bioorg Med Chem 17: 855-66 (2009)

More data for this
Ligand-Target Pair