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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sulfonylurea receptor 2, Kir6.2' and Ligand = 'BDBM50247765'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247765
PNG
((3S,4R) 4-[5-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-...)
Show SMILES CC1(C)Oc2ccncc2[C@H]([C@@H]1O)n1cncc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H18ClN3O2/c1-19(2)18(24)17(14-9-21-8-7-16(14)25-19)23-11-22-10-15(23)12-3-5-13(20)6-4-12/h3-11,17-18,24H,1-2H3/t17-,18+/m1/s1
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Article
PubMed
n/an/an/an/a 1.38E+4n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Bioorg Med Chem 17: 855-66 (2009)

More data for this
Ligand-Target Pair