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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sulfonylurea receptor 2, Kir6.2' and Ligand = 'BDBM50247775'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247775
PNG
((3S,4R)-3-Hydroxy-2,2-dimethyl-4-(4-oxo-1,4-dihydr...)
Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Nc2nc3ccccc3c(=O)[nH]2)[C@@H]1O)C#N
Show InChI InChI=1S/C20H18N4O3/c1-20(2)17(25)16(13-9-11(10-21)7-8-15(13)27-20)23-19-22-14-6-4-3-5-12(14)18(26)24-19/h3-9,16-17,25H,1-2H3,(H2,22,23,24,26)/t16-,17+/m1/s1
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Article
PubMed
n/an/an/an/a 3.71E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Citation and Details
More data for this
Ligand-Target Pair