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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sulfonylurea receptor 2, Kir6.2' and Ligand = 'BDBM50247799'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247799
PNG
((3S,4R)-4-(5-chloro-3-oxobenzo[d]isoxazol-2(3H)-yl...)
Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)n1oc2ccc(Cl)cc2c1=O)C#N
Show InChI InChI=1S/C19H15ClN2O4/c1-19(2)17(23)16(12-7-10(9-21)3-5-14(12)25-19)22-18(24)13-8-11(20)4-6-15(13)26-22/h3-8,16-17,23H,1-2H3/t16-,17+/m1/s1
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Article
PubMed
n/an/an/an/a 2.44E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Bioorg Med Chem 17: 855-66 (2009)

More data for this
Ligand-Target Pair