BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sulfonylurea receptor 2, Kir6.2' and Ligand = 'BDBM50247834'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247834
PNG
((3S,4R)-(5-Chloro-3-oxo-3H-benzo[d]isoxazol-2-yl)-...)
Show SMILES CCN(CC)S(=O)(=O)c1ccc2OC(C)(C)[C@@H](O)[C@@H](c2c1)n1oc2ccc(Cl)cc2c1=O
Show InChI InChI=1S/C22H25ClN2O6S/c1-5-24(6-2)32(28,29)14-8-10-17-15(12-14)19(20(26)22(3,4)30-17)25-21(27)16-11-13(23)7-9-18(16)31-25/h7-12,19-20,26H,5-6H2,1-4H3/t19-,20+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 820n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Bioorg Med Chem 17: 855-66 (2009)

More data for this
Ligand-Target Pair