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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sulfonylurea receptor 2, Kir6.2' and Ligand = 'BDBM50247907'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247907
PNG
((3S,4R)-4-(1,3-Dioxo-1,3-dihydro-pyrrolo[3,4-c]pyr...)
Show SMILES CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N1C(=O)c2ccncc2C1=O)C#N
Show InChI InChI=1S/C19H15N3O4/c1-19(2)16(23)15(12-7-10(8-20)3-4-14(12)26-19)22-17(24)11-5-6-21-9-13(11)18(22)25/h3-7,9,15-16,23H,1-2H3/t15-,16+/m1/s1
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PC cid
PC sid
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Similars

AffyNet 
Article
PubMed
n/an/an/an/a 6.04E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Citation and Details
More data for this
Ligand-Target Pair