Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50151352'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151352(5-(6-Methyl-[1,5]naphthyridin-4-yl)-4-pyridin-2-yl...)
Affinity DataIC50:  260nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151352(5-(6-Methyl-[1,5]naphthyridin-4-yl)-4-pyridin-2-yl...)
Affinity DataIC50:  380nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151352(5-(6-Methyl-[1,5]naphthyridin-4-yl)-4-pyridin-2-yl...)
Affinity DataIC50:  380nMAssay Description:Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.180-0.790)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed