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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor' and Ligand = 'BDBM50265108'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thrombopoietin receptor


(Homo sapiens)
BDBM50265108
PNG
(CHEMBL498581 | N-(7-(4-butylphenyl)-6-fluoro-5,10-...)
Show SMILES CCCCc1ccc(cc1)-c1ccc2c3Cc4cc(NC(C)=O)ccc4-c3[nH]c2c1F
Show InChI InChI=1S/C27H25FN2O/c1-3-4-5-17-6-8-18(9-7-17)21-12-13-23-24-15-19-14-20(29-16(2)31)10-11-22(19)26(24)30-27(23)25(21)28/h6-14,30H,3-5,15H2,1-2H3,(H,29,31)
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PC cid
PC sid
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Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 25n/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair