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Found 4 Enz. Inhib. hit(s) with Target = 'Thymidine kinase' and Ligand = 'BDBM21872'
TargetThymidine kinase(Human herpesvirus 2)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM21872(2,9-disubstituted 6-oxopurine, 6 | 9-(2-hydroxyeth...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 microM [3H]-thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21872(2,9-disubstituted 6-oxopurine, 6 | 9-(2-hydroxyeth...)
Affinity DataIC50:  2.20E+3nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1)
University Of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM21872(2,9-disubstituted 6-oxopurine, 6 | 9-(2-hydroxyeth...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of HSV-1 thymidine kinase, 1 microM [3H]-thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1)
Glsynthesis

LigandPNGBDBM21872(2,9-disubstituted 6-oxopurine, 6 | 9-(2-hydroxyeth...)
Affinity DataIC50:  4.40E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed