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Found 3 Enz. Inhib. hit(s) with Target = 'Thymidylate synthase' and Ligand = 'BDBM50011243'
TargetThymidylate synthase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50011243(2-{4-[(4-Hydroxy-quinazolin-6-ylmethyl)-prop-2-yny...)
Affinity DataKi:  26nMAssay Description:Binding affinity of the compound against thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011243(2-{4-[(4-Hydroxy-quinazolin-6-ylmethyl)-prop-2-yny...)
Affinity DataIC50:  160nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011243(2-{4-[(4-Hydroxy-quinazolin-6-ylmethyl)-prop-2-yny...)
Affinity DataIC50:  160nMAssay Description:Inhibitory concentration of compound to inhibit Thymidylate synthase (TS) in L1210 cells at conc. of 200 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed