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Found 4 Enz. Inhib. hit(s) with Target = 'Thymidylate synthase' and Ligand = 'BDBM50022737'
TargetThymidylate synthase(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50022737(2-{4-[(2-{(2-Amino-4-methyl-6-oxo-1,6-dihydro-pyri...)
Affinity DataKi:  37nMAssay Description:Inhibition of human thymidylate synthase at 600 uM concentration of 5,10-CH2-H4PteGluMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50022737(2-{4-[(2-{(2-Amino-4-methyl-6-oxo-1,6-dihydro-pyri...)
Affinity DataKi:  230nMAssay Description:Competitive inhibition of the human thymidylate synthase at 28 uM as Ki(slope) of 5,10-CH2-H4PteGluMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50022737(2-{4-[(2-{(2-Amino-4-methyl-6-oxo-1,6-dihydro-pyri...)
Affinity DataIC50:  350nMAssay Description:Competitive inhibition of the human thymidylate synthase at 28 uM of [dUMP]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50022737(2-{4-[(2-{(2-Amino-4-methyl-6-oxo-1,6-dihydro-pyri...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human thymidylate synthase at 600 uM concentration of 5,10-CH2-H4PteGluMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed