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Found 3 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 4' and Ligand = 'BDBM50029087'
TargetToll-like receptor 4(Mus musculus)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029087(CHEMBL3360819)
Affinity DataIC50:  800nMAssay Description:Antagonist activity at mouse TLR4 expressed in HEK293 cells co-transfected with mouse MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029087(CHEMBL3360819)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of LPS-induced TLR4 activation (unknown origin) expressed in HEK293 Blue cells compound treated for 30 mins prior LPS treatment measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029087(CHEMBL3360819)
Affinity DataIC50:  1.40E+3nMAssay Description:Antagonist activity at human TLR4 expressed in HEK293 cells co-transfected with human MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed