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Found 3 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM50189291'
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50189291(CHEMBL3827959 | US9597326, Compound 14)
Affinity DataEC50:  5.60E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells incubated for 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50189291(CHEMBL3827959 | US9597326, Compound 14)
Affinity DataEC50:  885nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetToll-like receptor 7(Mus musculus)
Genomics Institute Of Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50189291(CHEMBL3827959 | US9597326, Compound 14)
Affinity DataEC50:  1.40E+4nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed