Found 12 Enz. Inhib. hit(s) with Target = 'Trace amine-associated receptor 1' and Ligand = 'BDBM50359499' TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 1.50E+3nMAssay Description:Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 5.30E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 890nMAssay Description:Activation of rat TAAR1 expressed in HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 920nMAssay Description:Activation of mouse TAAR1 expressed in human HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Activation of mouse TAAR1 expressed in human HEK293 cells assessed as accumulation of cAMP after 15 minsMore data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 2.04E+3nMAssay Description:Activation of rat TAAR1 transmembrane domain 6 Met268(6.55)Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 202nMAssay Description:Activation of rat TAAR1 transmembrane domain 7 Asn287(7.39)Tyr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 18nMAssay Description:Activation of mouse TAAR1 transmembrane domain 6 Thr268(6.55)Met mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 279nMAssay Description:Activation of mouse wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 133nMAssay Description:Activation of rat wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 1.82E+3nMAssay Description:Activation of mouse TAAR1 transmembrane domain 7 Tyr287(7.39)Asn mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Activation of human TAAR1 expressed in human HEK293T cells assessed as cAMP accumulation after 10 mins by BRET assayMore data for this Ligand-Target Pair
