Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM50380687'
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica NV

Curated by ChEMBL
LigandPNGBDBM50380687(CHEMBL2017502)
Show SMILES CCOP(=O)(OCC)C(Cc1ccc(F)cc1)c1ccc2ccccc2c1
Show InChI InChI=1S/C22H24FO3P/c1-3-25-27(24,26-4-2)22(15-17-9-13-21(23)14-10-17)20-12-11-18-7-5-6-8-19(18)16-20/h5-14,16,22H,3-4,15H2,1-2H3
Affinity DataIC50: 120nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...More data for this Ligand-Target Pair