Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM50380689'
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica NV

Curated by ChEMBL
LigandPNGBDBM50380689(CHEMBL2017504)
Show SMILES CCOP(=O)(OCC)C(Cc1ccc(F)cc1)c1cc2ccccc2s1
Show InChI InChI=1S/C20H22FO3PS/c1-3-23-25(22,24-4-2)18(13-15-9-11-17(21)12-10-15)20-14-16-7-5-6-8-19(16)26-20/h5-12,14,18H,3-4,13H2,1-2H3
Affinity DataIC50: 250nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...More data for this Ligand-Target Pair