Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM50380705'
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica NV

Curated by ChEMBL
LigandPNGBDBM50380705(CHEMBL2017661)
Show SMILES CCOP(=O)(OCC)C(Cc1ccc(F)c(c1)C(F)(F)F)c1sc2ccccc2c1C
Show InChI InChI=1S/C22H23F4O3PS/c1-4-28-30(27,29-5-2)19(21-14(3)16-8-6-7-9-20(16)31-21)13-15-10-11-18(23)17(12-15)22(24,25)26/h6-12,19H,4-5,13H2,1-3H3
Affinity DataIC50: 120nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...More data for this Ligand-Target Pair