Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM50380706'
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica NV

Curated by ChEMBL
LigandPNGBDBM50380706(CHEMBL2017662)
Show SMILES CCOP(=O)(OCC)C(Cc1ccc(F)c(F)c1)c1cc2ccccc2s1
Show InChI InChI=1S/C20H21F2O3PS/c1-3-24-26(23,25-4-2)18(12-14-9-10-16(21)17(22)11-14)20-13-15-7-5-6-8-19(15)27-20/h5-11,13,18H,3-4,12H2,1-2H3
Affinity DataIC50: 390nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...More data for this Ligand-Target Pair