Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM50380707'
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica NV

Curated by ChEMBL
LigandPNGBDBM50380707(CHEMBL2017663)
Show SMILES CCOP(=O)(OCC)C(Cc1ccc(F)c(F)c1)c1sc2ccccc2c1C1CC1
Show InChI InChI=1S/C23H25F2O3PS/c1-3-27-29(26,28-4-2)20(14-15-9-12-18(24)19(25)13-15)23-22(16-10-11-16)17-7-5-6-8-21(17)30-23/h5-9,12-13,16,20H,3-4,10-11,14H2,1-2H3
Affinity DataIC50: 116nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...More data for this Ligand-Target Pair