Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM50380712'
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica NV

Curated by ChEMBL
LigandPNGBDBM50380712(CHEMBL2017670)
Show SMILES CCCP(=O)(CCC)C(Cc1ccc(F)c(F)c1)c1sc2ccccc2c1C
Show InChI InChI=1S/C23H27F2OPS/c1-4-12-27(26,13-5-2)21(15-17-10-11-19(24)20(25)14-17)23-16(3)18-8-6-7-9-22(18)28-23/h6-11,14,21H,4-5,12-13,15H2,1-3H3
Affinity DataIC50: 165nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...More data for this Ligand-Target Pair